|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:E-cadherin
gptkb:cadherin-1
|
|
gptkbp:antibodyTarget
|
yes
|
|
gptkbp:associatedWith
|
gptkb:hereditary_diffuse_gastric_cancer
gptkb:lobular_breast_cancer
|
|
gptkbp:discoveredBy
|
gptkb:Takeichi_M.
|
|
gptkbp:discoveredIn
|
1977
|
|
gptkbp:downregulationAssociatedWith
|
epithelial-mesenchymal transition
tumor progression
|
|
gptkbp:encodedBy
|
gptkb:CDH1_gene
|
|
gptkbp:Entrez_Gene_ID
|
999
|
|
gptkbp:foundIn
|
epithelial cells
|
|
gptkbp:function
|
cell-cell adhesion
maintenance of epithelial integrity
suppression of cancer metastasis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD324
|
|
gptkbp:interactsWith
|
gptkb:alpha-catenin
gptkb:p120-catenin
gptkb:beta-catenin
|
|
gptkbp:locatedOnChromosome
|
16q22.1
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
120 kDa
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
single-pass transmembrane protein
|
|
gptkbp:UniProtID
|
P12830
|
|
gptkbp:usedAs
|
immunohistochemical marker
|
|
gptkbp:bfsParent
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:bfsLayer
|
7
|