Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:FLT3
gptkb:Fms-like_tyrosine_kinase_3 |
| gptkbp:associatedWith |
gptkb:acute_myeloid_leukemia
|
| gptkbp:cellSurfaceMarker |
hematopoietic progenitor cells
|
| gptkbp:EC_number |
2.7.10.1
|
| gptkbp:encodedBy |
gptkb:FLT3_gene
|
| gptkbp:expressedIn |
bone marrow
lymphoid tissues |
| gptkbp:foundIn |
humans
|
| gptkbp:function |
gptkb:receptor_tyrosine_kinase
hematopoietic cell development |
| gptkbp:gene |
gptkb:FLT3
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD308
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_13q12
|
| gptkbp:molecularWeight |
~158 kDa
|
| gptkbp:mutationAssociatedWith |
poor prognosis in leukemia
|
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:target |
FLT3 inhibitors
|
| gptkbp:UniProtID |
P36888
|
| gptkbp:bfsParent |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:bfsLayer |
7
|