|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:B-lymphocyte_antigen_CD20
gptkb:Leu-16
gptkb:MS4A1
B1
|
|
gptkbp:antigen
|
differentiation antigen
|
|
gptkbp:associatedWith
|
leukemia
chronic lymphocytic leukemia
|
|
gptkbp:cellSurfaceMarker
|
yes
|
|
gptkbp:compatibleWith
|
gptkb:NK_cells
gptkb:pro-B_cells
gptkb:T_cells
platelets
erythrocytes
monocytes
plasma cells
hematopoietic stem cells
granulocytes
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
gptkb:MS4A1_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000156738
931
|
|
gptkbp:expressedIn
|
gptkb:pre-B_cells
mature B cells
follicular B cells
mantle zone B cells
marginal zone B cells
|
|
gptkbp:foundIn
|
gptkb:B_cells
|
|
gptkbp:function
|
B cell activation
B cell differentiation
B cell proliferation
regulation of calcium influx
|
|
gptkbp:HGNC_ID
|
7317
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD20
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11q12.2
|
|
gptkbp:membraneSpanningDomains
|
4
|
|
gptkbp:molecularWeight
|
33-37 kDa
|
|
gptkbp:OMIM
|
112210
|
|
gptkbp:structure
|
transmembrane protein
|
|
gptkbp:target
|
gptkb:rituximab
gptkb:ofatumumab
gptkb:obinutuzumab
|
|
gptkbp:UniProtID
|
P11836
|
|
gptkbp:usedAs
|
B cell marker
|
|
gptkbp:usedIn
|
immunophenotyping
diagnosis of B cell lymphomas
therapeutic antibody targeting
|
|
gptkbp:bfsParent
|
gptkb:rituximab
gptkb:small_lymphocytic_lymphoma
gptkb:B_lymphocytes
gptkb:B_cells
gptkb:Rituxan
gptkb:primary_mediastinal_large_B-cell_lymphoma
gptkb:primary_effusion_lymphoma
gptkb:Kesimpta
|
|
gptkbp:bfsLayer
|
6
|