|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:BST2
gptkb:HM1.24
gptkb:tetherin
|
|
gptkbp:antibodyTarget
|
therapeutic antibody development
|
|
gptkbp:discoveredBy
|
2008
|
|
gptkbp:encodedBy
|
gptkb:BST2_gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000130303
|
|
gptkbp:expressedIn
|
gptkb:B_cells
plasma cells
various cancer cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
involved in immune response
inhibits release of enveloped viruses
|
|
gptkbp:gene
|
gptkb:BST2
|
|
gptkbp:glycosylation
|
N-glycosylated
|
|
gptkbp:HGNC_ID
|
1119
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD317
|
|
gptkbp:interactsWith
|
gptkb:Vpu_protein_of_HIV-1
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19p13.2
|
|
gptkbp:location
|
gptkb:endoplasmic_reticulum
gptkb:Golgi_apparatus
cell surface
|
|
gptkbp:molecularWeight
|
~30-36 kDa
|
|
gptkbp:OMIM
|
610593
|
|
gptkbp:regulates
|
upregulated by interferon
|
|
gptkbp:role
|
immunotherapy
HIV-1 restriction
|
|
gptkbp:structure
|
type II transmembrane protein
|
|
gptkbp:UniProtID
|
Q10588
|
|
gptkbp:bfsParent
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:bfsLayer
|
7
|