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gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:Antigen_NY-CO-13
gptkb:Phosphoprotein_p53
gptkb:Tumor_suppressor_p53
gptkb:Transformation-related_protein_53
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gptkbp:associatedWith
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gptkb:Li-Fraumeni_syndrome
Various cancers
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gptkbp:biologicalProcess
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DNA repair
Transcription regulation
Apoptosis
DNA-binding
Cell cycle arrest
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gptkbp:database
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gptkb:UniProtKB/Swiss-Prot
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gptkbp:Entrez_Gene_ID
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7157
ENSG00000141510
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gptkbp:externalLink
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https://www.uniprot.org/uniprot/P23771
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gptkbp:function
|
Tumor suppressor
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gptkbp:gene
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gptkb:TP53
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gptkbp:GO
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gptkb:GO:0008285
GO:0003677
GO:0006355
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gptkbp:HGNC_ID
|
11998
|
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https://www.w3.org/2000/01/rdf-schema#label
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P23771
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gptkbp:interactsWith
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gptkb:CDKN1A
gptkb:CHEK2
gptkb:CREBBP
gptkb:EP300
gptkb:SIRT1
gptkb:SUMO1
gptkb:TP53BP1
gptkb:TP53BP2
gptkb:USP7
gptkb:FAS
gptkb:RB1
gptkb:BAX
gptkb:WWP1
gptkb:MDM2
gptkb:PTEN
gptkb:BRCA1
gptkb:E2F1
gptkb:GADD45A
gptkb:STAT3
gptkb:TP73
gptkb:YAP1
ATM
ZMAT3
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gptkbp:locatedOnChromosome
|
17
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gptkbp:locusType
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17p13.1
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gptkbp:mutationAssociatedWith
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R175H
R248Q
R273H
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gptkbp:OMIM
|
191170
|
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:orthologIn
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gptkb:Mouse_Trp53
gptkb:Zebrafish_tp53
Drosophila p53
Rat Trp53
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gptkbp:pathway
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DNA damage response
Apoptosis
Cell cycle
p53 signaling pathway
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gptkbp:PDB
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gptkb:2OCJ
gptkb:3KMD
gptkb:4HJE
1TUP
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gptkbp:postTranslationalModification
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Phosphorylation
Acetylation
Ubiquitination
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gptkbp:protein_name
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gptkb:Cellular_tumor_antigen_p53
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gptkbp:refersTo
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Human protein: Tumor protein p53
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gptkbp:RefSeq
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NP_000537.3
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gptkbp:sequence
|
393
|
|
gptkbp:status
|
Reviewed
|
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gptkbp:subcellularLocation
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gptkb:Mitochondrion
gptkb:Nucleus
gptkb:Cytoplasm
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gptkbp:UniProt_entry_name
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gptkb:P53_HUMAN
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gptkbp:bfsParent
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gptkb:GATA3
gptkb:ENSG00000111331
gptkb:ENSG00000111341
gptkb:ENSG00000113721
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gptkbp:bfsLayer
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7
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