|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
AIP2
Atrophin-1-interacting protein 2
NEDL1
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:domain
|
gptkb:WW_domain
gptkb:HECT_domain
|
|
gptkbp:encodes
|
WWP1 protein
|
|
gptkbp:Entrez_Gene_ID
|
11059
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
WW domain containing E3 ubiquitin protein ligase 1
|
|
gptkbp:function
|
E3 ubiquitin-protein ligase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WWP1
|
|
gptkbp:interactsWith
|
gptkb:SMURF2
Atrophin-1
NEDD4 family proteins
|
|
gptkbp:involvedIn
|
ubiquitin-dependent protein catabolic process
|
|
gptkbp:locatedOnChromosome
|
gptkb:8q21.3
|
|
gptkbp:molecularWeight
|
~110 kDa
|
|
gptkbp:OMIM
|
602307
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Wwp1
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
gptkb:SMAD2
gptkb:TGF-beta_signaling_pathway
gptkb:SMAD7
gptkb:PTEN
gptkb:p53
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:Q9H0M0
|
|
gptkbp:bfsParent
|
gptkb:NEDD4-1
|
|
gptkbp:bfsLayer
|
6
|