|
gptkbp:instanceOf
|
transcription factor
|
|
gptkbp:binds
|
GC-rich DNA sequences
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:domain
|
basic helix-span-helix domain
|
|
gptkbp:expressedIn
|
embryonic tissues
adult tissues
|
|
gptkbp:familyMember
|
gptkb:TFAP2A
gptkb:TFAP2B
gptkb:TFAP2C
gptkb:TFAP2D
gptkb:TFAP2E
|
|
gptkbp:foundIn
|
vertebrates
|
|
gptkbp:fullName
|
Activator Protein 2
|
|
gptkbp:gene
|
TFAP2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AP-2
|
|
gptkbp:involvedIn
|
apoptosis
cell differentiation
developmental processes
|
|
gptkbp:regulates
|
gptkb:CDKN1A
gptkb:EGFR
gptkb:NANOG
gptkb:ZEB2
gptkb:KLF4
gptkb:CDH1
gptkb:p21
gptkb:ERBB2
gptkb:ZEB1
gptkb:RET
gptkb:c-KIT
gptkb:CDKN1C
gptkb:OCT4
gptkb:SOX2
gptkb:BCL2
gptkb:CD44
gptkb:CDH2
gptkb:MMP2
gptkb:MMP9
gptkb:MYC
gptkb:SNAI1
gptkb:TP53
gptkb:L1CAM
gptkb:TWIST1
gptkb:VEGF
gptkb:E-cadherin
apoptosis
cell proliferation
differentiation
gene expression
cell growth
tumorigenesis
ITGB4
SNAI2
ITGA6
MCAM
|
|
gptkbp:structure
|
dimeric protein
|
|
gptkbp:bfsParent
|
gptkb:WAF1_gene
|
|
gptkbp:bfsLayer
|
6
|