|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:KIP2
gptkb:p57KIP2
CDI
|
|
gptkbp:associatedWith
|
gptkb:IMAGe_syndrome
gptkb:Beckwith-Wiedemann_syndrome
gptkb:Silver-Russell_syndrome
growth disorders
|
|
gptkbp:biologicalProcess
|
cell cycle arrest
negative regulation of cell proliferation
regulation of cell growth
cyclin-dependent protein serine/threonine kinase inhibitor activity
|
|
gptkbp:encodes
|
gptkb:cyclin-dependent_kinase_inhibitor_1C
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000129757
1028
|
|
gptkbp:expressedFromAllele
|
maternal
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
gptkb:cyclin_dependent_kinase_inhibitor_1C
|
|
gptkbp:function
|
cell cycle regulation
negative regulator of cell proliferation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
gptkb:CDKN1A
gptkb:CDKN1B
|
|
gptkbp:HGNC_ID
|
1786
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CDKN1C
|
|
gptkbp:imprintedGene
|
true
|
|
gptkbp:imprintingControlRegion
|
gptkb:ICR2_(KvDMR1)
|
|
gptkbp:length
|
316 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:molecularWeight
|
32 kDa
|
|
gptkbp:mutationAssociatedWith
|
growth restriction syndromes
overgrowth syndromes
|
|
gptkbp:OMIM
|
600856
|
|
gptkbp:orthologInMouse
|
gptkb:Cdkn1c
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:proteinFamily
|
gptkb:CIP/KIP_family
|
|
gptkbp:regulates
|
gptkb:KCNQ1OT1
apoptosis
cell differentiation
G1 phase of cell cycle
ICR2 methylation
cyclin/CDK complexes
tissue development
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P49918
|
|
gptkbp:bfsParent
|
gptkb:chromosome_11p15.5_(HRAS)
|
|
gptkbp:bfsLayer
|
5
|