Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
gptkb:Hirschsprung's_disease
gptkb:familial_medullary_thyroid_carcinoma gptkb:medullary_thyroid_carcinoma gptkb:multiple_endocrine_neoplasia_type_2 |
| gptkbp:discoveredIn |
1985
|
| gptkbp:encodes |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:Entrez_Gene_ID |
5979
|
| gptkbp:expressedIn |
neural crest-derived cells
|
| gptkbp:fullName |
REarranged during Transfection
|
| gptkbp:function |
cell growth and differentiation
|
| gptkbp:HGNC_ID |
9967
|
| https://www.w3.org/2000/01/rdf-schema#label |
RET
|
| gptkbp:length |
1114 amino acids
|
| gptkbp:locatedOnChromosome |
10q11.21
|
| gptkbp:mutationAssociatedWith |
gain-of-function
loss-of-function |
| gptkbp:OMIM |
164761
|
| gptkbp:orthologInMouse |
gptkb:Ret
|
| gptkbp:target |
gptkb:cabozantinib
gptkb:pralsetinib gptkb:selpercatinib gptkb:vandetanib |
| gptkbp:UniProtID |
P07949
|
| gptkbp:bfsParent |
gptkb:cancer
|
| gptkbp:bfsLayer |
4
|