|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Homeobox_transcription_factor_Nanog
gptkb:hNanog
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:NANOGNB
gptkb:NANOGP8
cancer stem cells
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:discoveredBy
|
gptkb:Austin_Smith
|
|
gptkbp:discoveredIn
|
2003
|
|
gptkbp:encodes
|
gptkb:Homeobox_protein_NANOG
|
|
gptkbp:Entrez_Gene_ID
|
79923
|
|
gptkbp:expressedIn
|
embryonic stem cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
maintenance of pluripotency
self-renewal of embryonic stem cells
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
20857
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NANOG
|
|
gptkbp:involvedIn
|
reprogramming somatic cells
stem cell differentiation
|
|
gptkbp:locatedOnChromosome
|
gptkb:12p13.31
gptkb:chromosome_12
|
|
gptkbp:marking
|
pluripotency
embryonic stem cells
|
|
gptkbp:molecularWeight
|
34 kDa
|
|
gptkbp:mutationAssociatedWith
|
germ cell tumors
teratocarcinoma
|
|
gptkbp:OMIM
|
607937
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
|
|
gptkbp:proteinFamily
|
homeobox proteins
|
|
gptkbp:regulates
|
gptkb:KLF4
gptkb:ESRRB
gptkb:OCT4
gptkb:SOX2
gptkb:Wnt_signaling
yes
TGF-beta signaling
pluripotency genes
|
|
gptkbp:sequence
|
305 amino acids
|
|
gptkbp:structure
|
contains homeodomain
|
|
gptkbp:UniProtID
|
Q9H9S0
|
|
gptkbp:usedIn
|
induced pluripotent stem cell generation
|
|
gptkbp:bfsParent
|
gptkb:chromosome_12
|
|
gptkbp:bfsLayer
|
6
|