|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
AP2-GAMMA
ERF-1
TFAP2C_HUMAN
|
|
gptkbp:associatedWith
|
gptkb:cancer
bladder cancer
germ cell tumors
|
|
gptkbp:binds
|
GC-rich DNA sequences
|
|
gptkbp:component
|
gptkb:nucleus
|
|
gptkbp:discoveredBy
|
researchers in the 1990s
|
|
gptkbp:encodes
|
AP-2 gamma protein
|
|
gptkbp:Entrez_Gene_ID
|
7026
ENSG00000137801
|
|
gptkbp:expressedIn
|
gptkb:placenta
gptkb:testis
breast tissue
|
|
gptkbp:fullName
|
Transcription factor AP-2 gamma
|
|
gptkbp:function
|
transcription factor
DNA-binding transcription factor activity
|
|
gptkbp:GOProcess
|
regulation of transcription, DNA-templated
|
|
gptkbp:HGNC_ID
|
HGNC:11743
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TFAP2C
|
|
gptkbp:length
|
450 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:20q13.2
chromosome 20
|
|
gptkbp:molecularWeight
|
49 kDa
|
|
gptkbp:mutationAssociatedWith
|
developmental disorders
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Tfap2c
|
|
gptkbp:regulates
|
gptkb:CDKN1A
gptkb:EGFR
gptkb:NANOG
gptkb:MUC1
gptkb:GATA3
gptkb:CDH1
gptkb:ERBB2
gptkb:FOXA1
gptkb:RET
gptkb:OCT4
gptkb:SOX2
gptkb:CD44
gptkb:AP-2_family
gptkb:KRT18
gptkb:KRT8
apoptosis
cell proliferation
differentiation
gene expression
CLDN7
KRT19
estrogen receptor alpha (ESR1)
|
|
gptkbp:UniProtID
|
Q92754
|
|
gptkbp:bfsParent
|
gptkb:AP2
gptkb:AP-2
|
|
gptkbp:bfsLayer
|
7
|