|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CEK2
gptkb:K-sam
gptkb:KGFR
gptkb:TK14
gptkb:BEK
gptkb:JWS
gptkb:CD332
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:encodes
|
gptkb:FGFR2_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000066468
2263
|
|
gptkbp:expressedIn
|
gptkb:cancer
mammary gland
stomach
intestine
epithelial cells
developing limb
mesenchymal cells
craniofacial tissue
|
|
gptkbp:fullName
|
gptkb:Fibroblast_growth_factor_receptor_2
|
|
gptkbp:function
|
gptkb:receptor_tyrosine_kinase
binds fibroblast growth factors
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3689
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGFR2
|
|
gptkbp:interactsWith
|
gptkb:PIK3R1
gptkb:PLCĪ³
gptkb:SHC1
gptkb:FGF1
gptkb:FGF2
gptkb:FGF7
gptkb:GRB2
gptkb:FGF10
gptkb:FRS2
|
|
gptkbp:involvedIn
|
cell differentiation
cell proliferation
embryonic development
|
|
gptkbp:locatedOnChromosome
|
10
|
|
gptkbp:location
|
gptkb:10q26
|
|
gptkbp:MIM_gene
|
176943
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Antley-Bixler_syndrome
gptkb:Apert_syndrome
gptkb:Beare-Stevenson_cutis_gyrata_syndrome
gptkb:Crouzon_syndrome
gptkb:Jackson-Weiss_syndrome
gptkb:endometrial_cancer
gptkb:Pfeiffer_syndrome
cholangiocarcinoma
gastric cancer
|
|
gptkbp:OMIM
|
176943
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Fgfr2
gptkb:zebrafish_fgfr2
|
|
gptkbp:pathway
|
gptkb:RAS_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:FGF_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:1EV2
gptkb:2PSQ
gptkb:2PVF
|
|
gptkbp:UniProtID
|
gptkb:P21802
|
|
gptkbp:bfsParent
|
gptkb:Lenvima
|
|
gptkbp:bfsLayer
|
5
|