Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
SNT
FRS2α SNT1 |
| gptkbp:domain |
multiple tyrosine phosphorylation sites
phosphotyrosine-binding domain |
| gptkbp:encodedBy |
FRS2 gene
|
| gptkbp:Entrez_Gene_ID |
10818
|
| gptkbp:fullName |
Fibroblast growth factor receptor substrate 2
|
| gptkbp:function |
adaptor protein in signal transduction
|
| gptkbp:gene |
gptkb:FRS2
|
| gptkbp:interactsWith |
gptkb:FGFR3
gptkb:FGFR1 gptkb:GRB2 gptkb:SOS1 gptkb:FGFR4 gptkb:FGFR2 Shp2 |
| gptkbp:locatedOnChromosome |
gptkb:12q15
|
| gptkbp:OMIM |
603830
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Frs2
|
| gptkbp:pathway |
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway gptkb:FGF_signaling_pathway |
| gptkbp:phosphorylates |
FGFR kinases
|
| gptkbp:role |
implicated in cancer
implicated in developmental disorders |
| gptkbp:subcellularLocation |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:UniProtID |
Q8WU20
|
| gptkbp:bfsParent |
gptkb:FGFR1
gptkb:FGFR2 |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
FRS2
|