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gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:ERBB
gptkb:ERBB1
mENA
NISBD2
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gptkbp:associatedWith
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gptkb:Glioblastoma
gptkb:Colorectal_cancer
Lung cancer
Non-small cell lung carcinoma
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gptkbp:biologicalProcess
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cell proliferation
signal transduction
ATP binding
protein tyrosine kinase activity
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gptkbp:citation
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gptkb:Reactome:_R-HSA-177929
ChEMBL: CHEMBL203
DrugBank: DB00002
Ensembl: ENSG00000146648
GeneID: 1956
HGNC: 3236
KEGG: hsa:1956
OMIM: 131550
PDB: 1M17
PharmGKB: PA162379175
UniProt: P21802
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gptkbp:database
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gptkb:UniProtKB/Swiss-Prot
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gptkbp:domain
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gptkb:Protein_kinase_domain
Furin-like cysteine-rich domain
L domain
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gptkbp:function
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Receptor tyrosine kinase involved in cell proliferation
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gptkbp:gene
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gptkb:EGFR
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gptkbp:hasIsoform
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Multiple
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https://www.w3.org/2000/01/rdf-schema#label
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P21802
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gptkbp:ligand
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gptkb:Heparin-binding_EGF-like_growth_factor
Amphiregulin
Betacellulin
Epiregulin
Transforming growth factor alpha
Epidermal growth factor
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gptkbp:locatedOnChromosome
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gptkb:7p11.2
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gptkbp:name
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gptkb:EGFR_HUMAN
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:orthologIn
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EGFR_CHICK
EGFR_MOUSE
EGFR_RAT
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gptkbp:pathway
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gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:ErbB_signaling_pathway
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gptkbp:postTranslationalModification
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Phosphorylation
Glycosylation
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gptkbp:protein_name
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gptkb:Epidermal_growth_factor_receptor
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gptkbp:refersTo
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gptkb:Epidermal_growth_factor_receptor
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gptkbp:sequence
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1210
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gptkbp:status
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Reviewed
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gptkbp:structure
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Single-pass type I membrane protein
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gptkbp:subcellularLocation
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gptkb:Endosome
gptkb:Nucleus
gptkb:Cell_membrane
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gptkbp:bfsParent
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gptkb:FGFR2
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gptkbp:bfsLayer
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6
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