SHC1

URI: https://gptkb.org/entity/SHC1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alias	gptkb:SHCA gptkb:SHC_(Src_Homology_2_Domain_Containing)_Transforming_Protein_1 gptkb:p66Shc
gptkbp:alternativeSplicing	gptkb:p46Shc gptkb:p52Shc gptkb:p66Shc
gptkbp:associatedWith	gptkb:cancer
gptkbp:discoveredBy	1992
gptkbp:domain	SH2 domain PTB domain
gptkbp:encodes	gptkb:SHC-transforming_protein_1
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000180008 6464
gptkbp:function	adaptor protein in signal transduction
gptkbp:gene	gptkb:SHC1
https://www.w3.org/2000/01/rdf-schema#label	SHC1
gptkbp:interactsWith	gptkb:EGFR gptkb:Insulin_receptor gptkb:Grb2 gptkb:SOS1
gptkbp:involves	gptkb:MAPK/ERK_pathway gptkb:PI3K/AKT_pathway
gptkbp:locatedOnChromosome	1q21.2
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:phosphorylates	tyrosine residues
gptkbp:UniProtID	gptkb:P29353
gptkbp:bfsParent	gptkb:GAB2 gptkb:Insulin_receptor gptkb:P42336 gptkb:PIK3R2 gptkb:PIK3R2_(p85β) gptkb:FGFR1 gptkb:GRB2 gptkb:FGFR2 gptkb:KEGG:_hsa04014
gptkbp:bfsLayer	6