|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ERBB
gptkb:ERBB1
gptkb:HER1
mENA
|
|
gptkbp:approvedBy
|
gptkb:epidermal_growth_factor_receptor
|
|
gptkbp:approvedSymbol
|
gptkb:EGFR
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
colorectal cancer
head and neck cancer
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000146648
1956
|
|
gptkbp:function
|
signal transduction
cell proliferation regulation
receptor tyrosine kinase activity
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3689
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC:3689
|
|
gptkbp:isProteinCoding
|
true
|
|
gptkbp:locatedOnChromosome
|
gptkb:7p11.2
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:locusType
|
gene with protein product
|
|
gptkbp:OMIM
|
131550
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Egfr
gptkb:rat_Egfr
gptkb:zebrafish_egfra
|
|
gptkbp:pathway
|
gptkb:EGFR_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:ErbB_signaling_pathway
|
|
gptkbp:previousSymbols
|
gptkb:ERBB
gptkb:ERBB1
gptkb:HER1
|
|
gptkbp:proteinFamily
|
protein tyrosine kinase
EGF receptor family
|
|
gptkbp:RefSeq
|
NM_005228
|
|
gptkbp:symbol
|
gptkb:EGFR
|
|
gptkbp:target
|
gptkb:afatinib
gptkb:cetuximab
gptkb:erlotinib
gptkb:gefitinib
gptkb:osimertinib
gptkb:necitumumab
gptkb:nimotuzumab
gptkb:dacomitinib
gptkb:lapatinib
gptkb:panitumumab
|
|
gptkbp:UniProtID
|
gptkb:P00533
|
|
gptkbp:bfsParent
|
gptkb:FGFR2
|
|
gptkbp:bfsLayer
|
6
|