Fibroblast growth factor receptor 2

URI: https://gptkb.org/entity/Fibroblast_growth_factor_receptor_2
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alternativeName gptkb:KGFR
gptkb:CD332
bek
gptkbp:associatedWith gptkb:Apert_syndrome
gptkb:Beare-Stevenson_cutis_gyrata_syndrome
gptkb:Crouzon_syndrome
gptkb:Jackson-Weiss_syndrome
gptkb:Pfeiffer_syndrome
gptkbp:biologicalProcess embryonic development
signal transduction
protein tyrosine kinase activity
skeletal development
gptkbp:cellularComponent gptkb:plasma_membrane
gptkbp:Entrez_Gene_ID gptkb:ENSG00000066468
gptkbp:expressedIn epithelial cells
gptkbp:function cell differentiation
angiogenesis
cell growth regulation
gptkbp:gene gptkb:FGFR2
gptkbp:hasIsoform gptkb:FGFR2b
gptkb:FGFR2c
gptkbp:HGNC_ID gptkb:HGNC:3689
https://www.w3.org/2000/01/rdf-schema#label Fibroblast growth factor receptor 2
gptkbp:ligand gptkb:fibroblast_growth_factors
gptkbp:locatedOnChromosome gptkb:10q26
gptkbp:mutationAssociatedWith craniosynostosis
gptkbp:OMIM 176943
gptkbp:orthologInMouse Fgfr2
gptkbp:PDB gptkb:2PSQ
gptkbp:UniProtID gptkb:P21802
gptkbp:bfsParent gptkb:FGFR2
gptkbp:bfsLayer 6