|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Heparin-binding_growth_factor_4
gptkb:K-FGF
HBGF-4
|
|
gptkbp:discoveredIn
|
gptkb:mouse
|
|
gptkbp:encodedBy
|
gptkb:FGF4_gene
|
|
gptkbp:Entrez_Gene_ID
|
2249
|
|
gptkbp:expressedIn
|
gptkb:placenta
gptkb:testis
embryonic stem cells
developing limb bud
|
|
gptkbp:family
|
gptkb:fibroblast_growth_factor_family
|
|
gptkbp:fullName
|
gptkb:Fibroblast_growth_factor_4
|
|
gptkbp:function
|
cell differentiation
embryonic development
cell growth
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO
|
GO:0007267 (cell-cell signaling)
GO:0008083 (growth factor activity)
|
|
gptkbp:HGNC_ID
|
3667
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGF4
|
|
gptkbp:length
|
206 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11q13
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
limb malformations
|
|
gptkbp:OMIM
|
164980
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Fgf4
gptkb:rat_Fgf4
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:FGF_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:1BLA
gptkb:1FGA
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:recipient
|
gptkb:FGFR3
gptkb:FGFR1
gptkb:FGFR4
gptkb:FGFR2
|
|
gptkbp:regulates
|
regulated by OCT4
regulated by SOX2
upregulated by Wnt signaling
|
|
gptkbp:relatedTo
|
angiogenesis
tumorigenesis
limb development
mesoderm induction
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:structure
|
monomer
|
|
gptkbp:UniProtID
|
P08620
|
|
gptkbp:bfsParent
|
gptkb:FGFR1
gptkb:Sox2
|
|
gptkbp:bfsLayer
|
6
|