Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
various cancers
|
| gptkbp:can_metastasize_to |
gain-of-function mutations
loss-of-function mutations |
| gptkbp:has_method |
cell signaling
|
| gptkbp:has_role |
gptkb:project
|
| https://www.w3.org/2000/01/rdf-schema#label |
FGFR
|
| gptkbp:is_associated_with |
therapeutic resistance
|
| gptkbp:is_involved_in |
apoptosis
cell differentiation cell proliferation immune response metabolic disorders signal transduction pathways wound healing chondrogenesis cell survival tumor microenvironment extracellular matrix remodeling eye development neurogenesis organogenesis angiogenesis tissue repair cell adhesion cell migration metastasis tooth development vascular development tissue homeostasis hair follicle development osteogenesis kidney development endothelial cell function heart development lung development neural crest development placenta development neurodevelopment neovascularization cardiogenesis germ layer formation myogenesis axis formation skin development gastrointestinal development ear development fibroblast function skeletal disorders |
| gptkbp:is_linked_to |
disease progression
|
| gptkbp:is_part_of |
fibroblast growth factor receptor family
|
| gptkbp:is_represented_in |
various tissues
adult stem cells embryonic stem cells |
| gptkbp:is_studied_in |
clinical trials
|
| gptkbp:promoter |
FGF R1
FGF R2 FGF R3 FGF R4 |
| gptkbp:regulates |
fibroblast growth factors
|
| gptkbp:targets |
FGFR inhibitors
|
| gptkbp:bfsParent |
gptkb:receptor_tyrosine_kinase
gptkb:Lenvatinib |
| gptkbp:bfsLayer |
5
|