|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
aFGF
acidic fibroblast growth factor
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
embryonic development
angiogenesis
neurogenesis
tissue regeneration
|
|
gptkbp:discoveredBy
|
Gospodarowicz D.
|
|
gptkbp:discoveredIn
|
1974
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gptkbp:encodedBy
|
FGF1 gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000113578
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:kidney
brain
liver
endothelial cells
|
|
gptkbp:family
|
gptkb:fibroblast_growth_factor_family
|
|
gptkbp:fullName
|
Fibroblast growth factor 1
|
|
gptkbp:function
|
wound healing
angiogenesis
cell growth
tissue repair
mitogenic activity
|
|
gptkbp:gene
|
gptkb:FGF1
|
|
gptkbp:GOID
|
GO:0008083
|
|
gptkbp:HGNC_ID
|
3665
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGF1
|
|
gptkbp:interactsWith
|
gptkb:FGFR3
gptkb:FGFR1
gptkb:heparan_sulfate_proteoglycans
gptkb:FGFR4
gptkb:FGFR2
|
|
gptkbp:length
|
155 amino acids
|
|
gptkbp:locatedOnChromosome
|
5q31.3
|
|
gptkbp:molecularWeight
|
17 kDa
|
|
gptkbp:OMIM
|
131220
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
gptkb:FGF_signaling_pathway
|
|
gptkbp:PDB
|
1RG8
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:recipient
|
gptkb:FGFR3
gptkb:FGFR1
gptkb:FGFR4
gptkb:FGFR2
|
|
gptkbp:RefSeq
|
NM_002006
|
|
gptkbp:significance
|
gptkb:cancer
wound healing
neurodegenerative diseases
angiogenesis-related diseases
|
|
gptkbp:structure
|
beta-trefoil fold
|
|
gptkbp:UniProtID
|
P05230
|
|
gptkbp:bfsParent
|
gptkb:FGFR3
gptkb:FGFR1
gptkb:FGFR2
|
|
gptkbp:bfsLayer
|
6
|