Statements (65)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:Oncology
|
| gptkbp:code |
GRB2 gene on chromosome 17
|
| gptkbp:function |
adaptor protein
|
| gptkbp:has_binding_site |
phosphotyrosine residues
|
| gptkbp:has_role |
apoptosis
cell differentiation cell proliferation |
| https://www.w3.org/2000/01/rdf-schema#label |
GRB2
|
| gptkbp:interacts_with |
gptkb:SOS1
gptkb:EGFR |
| gptkbp:involved_in |
Ras signaling pathway
cell signaling |
| gptkbp:is_associated_with |
gptkb:diabetes
cardiovascular diseases |
| gptkbp:is_expressed_in |
various tissues
|
| gptkbp:is_involved_in |
cell cycle regulation
cellular homeostasis cellular metabolism cellular stress response cytoskeletal organization developmental processes immune response metabolic processes signal transduction wound healing stress response neuronal signaling cell survival cellular aging endocytosis angiogenesis immune cell activation cell adhesion cell migration metastasis cellular communication exocytosis tumor progression signal amplification cellular repair mechanisms cellular differentiation pathways cellular energy production cellular signaling networks cellular transport mechanisms cellular waste management hormonal signaling cellular detoxification growth factor signaling cytokine signaling cellular response to stimuli neurotransmitter signaling receptor signaling growth regulation |
| gptkbp:is_part_of |
Ras-MAPK pathway
|
| gptkbp:is_regulated_by |
phosphorylation
|
| gptkbp:is_studied_in |
cancer research
|
| gptkbp:located_in |
cytoplasm
|
| gptkbp:orthologs |
in various species
|
| gptkbp:promoter |
GRB2 gene
|
| gptkbp:research |
SH2 domain
SH3 domain |
| gptkbp:targets |
drug development
|
| gptkbp:bfsParent |
gptkb:EGFR
|
| gptkbp:bfsLayer |
5
|