Statements (63)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:healthcare_organization
|
| gptkbp:can_lead_to |
dimerization
|
| gptkbp:caused_by |
tumorigenesis
|
| gptkbp:established |
signal transduction pathways
ligand binding tyrosine kinase inhibitors |
| gptkbp:example |
gptkb:FGFR
gptkb:VEGFR gptkb:EGFR gptkb:PDGFR |
| gptkbp:function |
cell signaling
|
| gptkbp:has_role |
gptkb:embryonic_development
|
| gptkbp:has_website |
tyrosine kinase domain
|
| https://www.w3.org/2000/01/rdf-schema#label |
receptor tyrosine kinase
|
| gptkbp:is_associated_with |
gptkb:Company
|
| gptkbp:is_essential_for |
normal cellular function
|
| gptkbp:is_involved_in |
apoptosis
cell cycle regulation cell differentiation cell growth cellular homeostasis immune response metabolic pathways neurotransmitter release wound healing cell survival neural development neurogenesis angiogenesis immune cell activation tissue repair cell migration stem cell maintenance metabolism regulation vascular development signal amplification hormonal signaling cellular responses to stress extracellular matrix interaction cellular responses to cytokines cellular responses to electrical signals cellular responses to growth factors cellular responses to hormones cellular responses to light cellular responses to mechanical stress cellular responses to temperature changes cellular responses to nutrients cellular responses to oxygen levels cellular responses to ion concentrations cellular responses to p H changes |
| gptkbp:is_linked_to |
metastasis
|
| gptkbp:is_part_of |
growth factor signaling
receptor signaling complex |
| gptkbp:is_represented_in |
various tissues
|
| gptkbp:is_studied_in |
biomedical research
|
| gptkbp:location |
cell membrane
|
| gptkbp:regulates |
phosphorylation
|
| gptkbp:targets |
cancer therapies
|
| gptkbp:type |
gptkb:physicist
|
| gptkbp:bfsParent |
gptkb:EGFR
gptkb:Trk_B._T1 |
| gptkbp:bfsLayer |
4
|