Statements (22)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:DNA
|
gptkbp:associated_with |
telomere length
|
gptkbp:code |
gptkb:telomerase_reverse_transcriptase
|
gptkbp:discovered_by |
1990s
|
gptkbp:function |
adds DNA sequence repeats to telomeres
|
gptkbp:genetic_studies |
certain cancers
|
gptkbp:has_role |
cell proliferation
|
gptkbp:has_variants |
TERT promoter mutations
|
https://www.w3.org/2000/01/rdf-schema#label |
TERT
|
gptkbp:interacts_with |
TERC
|
gptkbp:involved_in |
cellular aging
|
gptkbp:is_essential_for |
immortalization of cells
|
gptkbp:is_expressed_in |
gptkb:Cell
germ cells |
gptkbp:is_involved_in |
DNA repair mechanisms
|
gptkbp:is_linked_to |
age-related diseases
|
gptkbp:is_part_of |
telomerase complex
|
gptkbp:is_regulated_by |
gptkb:telomerase_RNA_component_(TERC)
|
gptkbp:is_studied_in |
cancer research
|
gptkbp:is_targeted_at |
telomerase inhibitors
|
gptkbp:located_in |
human chromosome 5
|
gptkbp:regulates |
telomere maintenance
|