TERT

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instance_of gptkb:DNA
gptkbp:associated_with telomere length
gptkbp:code gptkb:telomerase_reverse_transcriptase
gptkbp:discovered_by 1990s
gptkbp:function adds DNA sequence repeats to telomeres
gptkbp:genetic_studies certain cancers
gptkbp:has_role cell proliferation
gptkbp:has_variants TERT promoter mutations
https://www.w3.org/2000/01/rdf-schema#label TERT
gptkbp:interacts_with TERC
gptkbp:involved_in cellular aging
gptkbp:is_essential_for immortalization of cells
gptkbp:is_expressed_in gptkb:Cell
germ cells
gptkbp:is_involved_in DNA repair mechanisms
gptkbp:is_linked_to age-related diseases
gptkbp:is_part_of telomerase complex
gptkbp:is_regulated_by gptkb:telomerase_RNA_component_(TERC)
gptkbp:is_studied_in cancer research
gptkbp:is_targeted_at telomerase inhibitors
gptkbp:located_in human chromosome 5
gptkbp:regulates telomere maintenance