Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
transcription factor |
| gptkbp:activatedBy |
oxidative stress
|
| gptkbp:alternativeName |
gptkb:FOXO3
gptkb:FKHRL1 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:diabetes longevity |
| gptkbp:encodedBy |
FOXO3 gene
|
| gptkbp:function |
apoptosis
cell cycle regulation regulation of gene expression oxidative stress response |
| https://www.w3.org/2000/01/rdf-schema#label |
FOXO3a
|
| gptkbp:inhibitedBy |
insulin signaling
|
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
gptkb:6q21
|
| gptkbp:memberOf |
gptkb:FOXO_family
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:phosphorylates |
gptkb:AKT
inactive in cytoplasm |
| gptkbp:phosphorylationEffect |
nuclear export
|
| gptkbp:regulates |
gptkb:GADD45
gptkb:MnSOD gptkb:p27Kip1 BIM catalase |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
O43524
|
| gptkbp:unphosphorylatedForm |
active in nucleus
|
| gptkbp:bfsParent |
gptkb:SGK1
|
| gptkbp:bfsLayer |
7
|