|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Antigen_NY-CO-13
gptkb:Phosphoprotein_p53
gptkb:Tumor_suppressor_p53
gptkb:Transformation-related_protein_53
|
|
gptkbp:associatedWith
|
gptkb:Li-Fraumeni_syndrome
various cancers
|
|
gptkbp:discoveredBy
|
gptkb:Arnold_J._Levine
gptkb:David_P._Lane
gptkb:Lloyd_J._Old
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:EC_number
|
2.7.7.7
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:TP53
gptkb:ENSP00000269305
7157
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:function
|
gptkb:transcription_factor
gptkb:tumor_suppressor
induces apoptosis
DNA binding
regulates cell cycle
|
|
gptkbp:gene
|
gptkb:TP53
|
|
gptkbp:hasIsoform
|
multiple
|
|
gptkbp:HGNC_ID
|
11998
|
|
gptkbp:InterPro
|
gptkb:IPR002117
gptkb:IPR011615
|
|
gptkbp:KEGGID
|
gptkb:hsa:7157
|
|
gptkbp:length
|
393
|
|
gptkbp:locatedOnChromosome
|
17
17p13.1
|
|
gptkbp:molecularWeight
|
43928
|
|
gptkbp:OMIM
|
191170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Trp53
gptkb:rat_Tp53
gptkb:zebrafish_tp53
|
|
gptkbp:PDB
|
gptkb:2OCJ
gptkb:3KMD
1TUP
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
sumoylation
ubiquitination
acetylation
|
|
gptkbp:protein_name
|
gptkb:Cellular_tumor_antigen_p53
|
|
gptkbp:proteinFamily
|
gptkb:PF00870
|
|
gptkbp:Reactome
|
gptkb:R-HSA-69563
|
|
gptkbp:RefSeq
|
NP_000537.3
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniGene
|
Hs.476226
|
|
gptkbp:UniProtID
|
gptkb:P04629
|
|
gptkbp:bfsParent
|
gptkb:TrkA
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P04629
|