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gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:ERBB
gptkb:ERBB1
gptkb:HER1
mENA
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gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
colorectal cancer
|
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gptkbp:biologicalProcess
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cell differentiation
cell proliferation
signal transduction
ATP binding
protein tyrosine kinase activity
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gptkbp:cellularComponent
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gptkb:plasma_membrane
|
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gptkbp:function
|
Receptor tyrosine kinase involved in the regulation of cell growth and differentiation
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gptkbp:gene
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gptkb:EGFR
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gptkbp:HGNC_ID
|
3236
|
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https://www.w3.org/2000/01/rdf-schema#label
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P42336
|
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gptkbp:interactsWith
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gptkb:CBL
gptkb:ERBB3
gptkb:PIK3R1
gptkb:SHC1
gptkb:SRC
gptkb:ERBB2
gptkb:GRB2
gptkb:STAT3
gptkb:ERBB4
|
|
gptkbp:locatedOnChromosome
|
7
|
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gptkbp:locusType
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gptkb:7p11.2
|
|
gptkbp:organism
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gptkb:Homo_sapiens
9606
|
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gptkbp:pathway
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gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:ErbB_signaling_pathway
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gptkbp:PDB
|
1M17
2GS6
2ITX
3POZ
4HJO
4KRL
5HG7
5JEB
5UG9
6JXT
|
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gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
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gptkbp:protein_existence
|
Evidence at protein level
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gptkbp:refersTo
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gptkb:Epidermal_growth_factor_receptor
|
|
gptkbp:RefSeq
|
NP_005219.2
|
|
gptkbp:sequence
|
1210
|
|
gptkbp:subcellularLocation
|
gptkb:endosome
gptkb:cell_membrane
gptkb:nucleus
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gptkbp:UniProt_entry_name
|
gptkb:EGFR_HUMAN
|
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gptkbp:UniProtID
|
gptkb:P42336
ENSP00000275493
|
|
gptkbp:bfsParent
|
gptkb:PIK3CA
|
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gptkbp:bfsLayer
|
5
|