|
gptkbp:instanceOf
|
gptkb:UniProt_accession_number
|
|
gptkbp:alternativeName
|
gptkb:ERBB
gptkb:ERBB1
gptkb:HER1
mENA
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
colorectal cancer
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
signal transduction
ATP binding
protein tyrosine kinase activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:function
|
Receptor tyrosine kinase involved in the regulation of cell growth and differentiation
|
|
gptkbp:gene
|
gptkb:EGFR
|
|
gptkbp:HGNC_ID
|
3236
|
|
gptkbp:interactsWith
|
gptkb:CBL
gptkb:ERBB3
gptkb:PIK3R1
gptkb:SHC1
gptkb:SRC
gptkb:ERBB2
gptkb:GRB2
gptkb:STAT3
gptkb:ERBB4
|
|
gptkbp:locatedOnChromosome
|
7
|
|
gptkbp:locusType
|
gptkb:7p11.2
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
9606
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:ErbB_signaling_pathway
|
|
gptkbp:PDB
|
1M17
2GS6
2ITX
3POZ
4HJO
4KRL
5HG7
5JEB
5UG9
6JXT
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:protein_existence
|
Evidence at protein level
|
|
gptkbp:refersTo
|
gptkb:Epidermal_growth_factor_receptor
|
|
gptkbp:RefSeq
|
NP_005219.2
|
|
gptkbp:sequence
|
1210
|
|
gptkbp:subcellularLocation
|
gptkb:endosome
gptkb:cell_membrane
gptkb:nucleus
|
|
gptkbp:UniProt_entry_name
|
gptkb:EGFR_HUMAN
|
|
gptkbp:UniProtID
|
gptkb:P42336
ENSP00000275493
|
|
gptkbp:bfsParent
|
gptkb:PIK3CA
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P42336
|