Statements (168)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:EGFR
|
| gptkbp:associatedWith |
gptkb:non-small_cell_lung_cancer
gptkb:glioblastoma colorectal cancer |
| gptkbp:biologicalProcess |
cell proliferation
signal transduction protein tyrosine kinase activity |
| gptkbp:cellularComponent |
gptkb:plasma_membrane
|
| gptkbp:containsGene |
gptkb:EGFR
|
| gptkbp:domain |
transmembrane domain
extracellular ligand-binding domain tyrosine kinase domain |
| https://www.w3.org/2000/01/rdf-schema#label |
P00533
|
| gptkbp:isReceptorFor |
gptkb:epidermal_growth_factor
gptkb:transforming_growth_factor_alpha |
| gptkbp:length |
1210 amino acids
|
| gptkbp:ligand |
gptkb:epidermal_growth_factor
gptkb:transforming_growth_factor_alpha |
| gptkbp:locatedOnChromosome |
gptkb:7p11.2
gptkb:chromosome_7 |
| gptkbp:molecularWeight |
134 kDa
|
| gptkbp:name |
gptkb:Epidermal_growth_factor_receptor
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:4ZAU
gptkb:6LUB gptkb:7UKV gptkb:7AEM 1M17 2GS6 2ITX 4HJO 5HG7 5JEB 5UG9 6JXT 7JX0 7TVD 7V6Q 7V6R 7V6S 7V6T 7V6U 7V6V 7V6W 7V6X 7V6Y 7V6Z 7V70 7V71 7V72 7V73 7V74 7V75 7V76 7V77 7V78 7V79 7V7A 7V7B 7V7C 7V7D 7V7E 7V7F 7V7G 7V7H 7V7I 7V7J 7V7K 7V7L 7V7M 7V7N 7V7O 7V7P 7V7Q 7V7R 7V7S 7V7T 7V7U 7V7V 7V7W 7V7X 7V7Y 7V7Z 7V80 7V81 7V82 7V83 7V84 7V85 7V86 7V87 7V88 7V89 7V8A 7V8B 7V8C 7V8D 7V8E 7V8F 7V8G 7V8H 7V8I 7V8J 7V8K 7V8L 7V8M 7V8N 7V8O 7V8P 7V8Q 7V8R 7V8S 7V8T 7V8U 7V8V 7V8W 7V8X 7V8Y 7V8Z 7V90 7V91 7V92 7V93 7V94 7V95 7V96 7V97 7V98 7V99 7V9A 7V9B 7V9C 7V9D 7V9E 7V9F 7V9G 7V9H 7V9I 7V9J 7V9K 7V9L 7V9M 7V9N 7V9O 7V9P 7V9Q 7V9R 7V9S 7V9T 7V9U 7V9V 7V9W 7V9X 7V9Y 7V9Z |
| gptkbp:RefSeq |
NP_005219.2
|
| gptkbp:targetOfDrug |
gptkb:afatinib
gptkb:cetuximab gptkb:erlotinib gptkb:gefitinib gptkb:osimertinib |
| gptkbp:UniProtID |
gptkb:P00533
ENSP00000275493 |
| gptkbp:bfsParent |
gptkb:EGFR
gptkb:EGFR_gene gptkb:NP_005334.1 |
| gptkbp:bfsLayer |
6
|