Fibroblast growth factor receptor 3

URI: https://gptkb.org/entity/Fibroblast_growth_factor_receptor_3
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alternativeSplicing produces multiple isoforms
gptkbp:biologicalProcess protein tyrosine kinase activity
gptkbp:cellularComponent gptkb:plasma_membrane
gptkbp:discoveredBy researchers in the 1990s
gptkbp:Entrez_Gene_ID gptkb:ENSG00000068078
gptkbp:expressedIn gptkb:kidney
brain
collagen
gptkbp:function cell differentiation
cell growth regulation
skeletal development
gptkbp:gene gptkb:FGFR3
gptkbp:HGNC_ID gptkb:HGNC:3689
https://www.w3.org/2000/01/rdf-schema#label Fibroblast growth factor receptor 3
gptkbp:ligand fibroblast growth factor
gptkbp:locatedOnChromosome gptkb:4p16.3
gptkbp:mutationAssociatedWith gptkb:cancer
gptkb:hypochondroplasia
gptkb:thanatophoric_dysplasia
multiple myeloma
bladder cancer
achondroplasia
gptkbp:OMIM 134934
gptkbp:orthologInMouse Fgfr3
gptkbp:pathway gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkbp:PDB gptkb:4K33
gptkbp:UniProtID gptkb:P22607
gptkbp:bfsParent gptkb:FGFR3
gptkbp:bfsLayer 6