Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:monoclonal_antibody
|
| gptkbp:administeredBy |
intravenous infusion
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA 2015 |
| gptkbp:ATCCode |
L01XC28
|
| gptkbp:brand |
Portrazza
|
| gptkbp:CASNumber |
906805-79-2
|
| gptkbp:developedBy |
gptkb:Eli_Lilly_and_Company
|
| https://www.w3.org/2000/01/rdf-schema#label |
necitumumab
|
| gptkbp:indication |
metastatic squamous non-small cell lung cancer
|
| gptkbp:macromoleculeType |
gptkb:IgG1
|
| gptkbp:mechanismOfAction |
EGFR inhibition
|
| gptkbp:notRecommendedFor |
non-squamous non-small cell lung cancer
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
skin rash
hypomagnesemia thromboembolic events |
| gptkbp:target |
gptkb:EGFR
|
| gptkbp:UNII |
6Y7T5M4A6F
|
| gptkbp:usedFor |
gptkb:non-small_cell_lung_cancer
|
| gptkbp:bfsParent |
gptkb:EGFR_protein
gptkb:HGNC:3689 gptkb:HGNC:3767 |
| gptkbp:bfsLayer |
7
|