|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CEK2
gptkb:KGFR
gptkb:TK14
gptkb:bFGF-R
gptkb:BEK
gptkb:CD332
TK25
fibroblast growth factor receptor 2 precursor
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Endometrial_cancer
gptkb:Antley-Bixler_syndrome
gptkb:Apert_syndrome
gptkb:Beare-Stevenson_cutis_gyrata_syndrome
gptkb:Crouzon_syndrome
gptkb:Jackson-Weiss_syndrome
gptkb:Pfeiffer_syndrome
Breast cancer
|
|
gptkbp:discoveredBy
|
Ullrich et al.
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:encodes
|
gptkb:FGFR2_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000066468
2263
|
|
gptkbp:expressedIn
|
gptkb:thyroid
gptkb:cancer
gptkb:bone
gptkb:skin
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
brain
heart
liver
spleen
colon
pancreas
stomach
epithelial cells
mesenchymal cells
lung epithelium
|
|
gptkbp:fullName
|
fibroblast growth factor receptor 2
|
|
gptkbp:function
|
cell differentiation
angiogenesis
cell growth regulation
receptor tyrosine kinase activity
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3689
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGFR2 gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:10q26
10
|
|
gptkbp:mutationAssociatedWith
|
nonsense
deletion
missense
duplication
|
|
gptkbp:numberOfExons
|
18
|
|
gptkbp:OMIM
|
176943
|
|
gptkbp:orthologInMouse
|
Fgfr2
|
|
gptkbp:pathway
|
gptkb:RAS_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:proteinFamily
|
fibroblast growth factor receptor family
|
|
gptkbp:UniProtID
|
gptkb:P21802
|
|
gptkbp:bfsParent
|
gptkb:FGFR
|
|
gptkbp:bfsLayer
|
6
|