B cell receptor signaling pathway

GPTKB entity

Predicate	Object
gptkbp:instanceOf	biological pathway
gptkbp:activatedBy	gptkb:BLNK_adaptor_protein gptkb:Lyn_kinase gptkb:Syk_kinase gptkb:protein_tyrosine_kinases
gptkbp:cause	gene transcription NF-κB activation activation of MAPK pathway activation of PI3K activation of PLCγ2 calcium mobilization
gptkbp:describedBy	gptkb:Gene_Ontology:_GO:0050853
gptkbp:hasComponent	gptkb:Akt gptkb:IP3 gptkb:CD22 gptkb:CD45 gptkb:BCR_complex gptkb:Btk_(Bruton's_tyrosine_kinase) gptkb:Erk gptkb:IκB gptkb:Igα_(CD79A) gptkb:Igβ_(CD79B) gptkb:NFAT gptkb:PKCβ gptkb:Grb2 gptkb:calmodulin gptkb:Vav gptkb:JNK gptkb:p38_MAPK gptkb:DAG gptkb:Ras gptkb:CD19 gptkb:CD21 gptkb:CD81 gptkb:SHIP gptkb:NF-κB gptkb:AP-1 gptkb:Fyn_kinase gptkb:SHP-1 calcium ions
gptkbp:hasDiseaseAssociation	autoimmune diseases B cell lymphomas
https://www.w3.org/2000/01/rdf-schema#label	B cell receptor signaling pathway
gptkbp:involves	B cell receptor antigen binding
gptkbp:partOf	adaptive immune response humoral immunity
gptkbp:regulates	B cell differentiation B cell proliferation B cell survival
gptkbp:bfsParent	gptkb:tyrosine-protein_kinase_Tec
gptkbp:bfsLayer	6