|
gptkbp:instanceOf
|
transcription factor
|
|
gptkbp:activatedBy
|
cytokines
growth factors
phorbol esters
stress signals
|
|
gptkbp:alternativeName
|
gptkb:Activator_Protein_1
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:composedOf
|
gptkb:Fos_protein_family
gptkb:Jun_protein_family
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:encodedBy
|
gptkb:FOS_gene
gptkb:JUN_gene
|
|
gptkbp:form
|
heterodimers
homodimers
|
|
gptkbp:hasRole
|
inflammation
immune response
oncogenesis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AP-1
|
|
gptkbp:involvedIn
|
apoptosis
cell proliferation
differentiation
|
|
gptkbp:locatedIn
|
gptkb:nucleus
|
|
gptkbp:recognizedBy
|
gptkb:TRE_(TPA_response_element)
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:studiedIn
|
cancer research
immunology
neuroscience
|
|
gptkbp:subunit
|
gptkb:c-Jun
gptkb:FosB
gptkb:Fra-1
gptkb:Fra-2
gptkb:JunD
gptkb:c-Fos
gptkb:JunB
|
|
gptkbp:target
|
gptkb:JNK_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:p38_MAPK_pathway
gptkb:ERK_signaling_pathway
|
|
gptkbp:bfsParent
|
gptkb:c-Jun
gptkb:Tnf
gptkb:Euroroute_E5
gptkb:B_cell_receptor_signaling_pathway
gptkb:CCND1
gptkb:IL6_gene
|
|
gptkbp:bfsLayer
|
7
|