Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:HCP
gptkb:PTP-1C Hematopoietic cell phosphatase PTPN6 protein |
| gptkbp:domain |
SH2 domain
phosphatase domain |
| gptkbp:enzymeCommissionNumber |
EC 3.1.3.48
|
| gptkbp:expressedIn |
hematopoietic cells
|
| gptkbp:fullName |
Src homology region 2 domain-containing phosphatase-1
|
| gptkbp:function |
gptkb:protein_tyrosine_phosphatase
negative regulation of cell signaling |
| gptkbp:gene |
gptkb:PTPN6
|
| https://www.w3.org/2000/01/rdf-schema#label |
SHP-1
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
68 kDa
|
| gptkbp:mutationAssociatedWith |
leukemia
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Ptpn6
|
| gptkbp:regulates |
gptkb:JAK/STAT_pathway
immune cell signaling |
| gptkbp:UniProtID |
gptkb:P29350
|
| gptkbp:bfsParent |
gptkb:PTPN6
gptkb:B_cell_receptor_signaling_pathway |
| gptkbp:bfsLayer |
7
|