|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
tyrosine-protein kinase
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
multiple sclerosis
autoimmune diseases
|
|
gptkbp:biologicalProcess
|
gptkb:T_cell_receptor_signaling_pathway
immune response
neuronal development
cell adhesion
protein tyrosine kinase activity
axon guidance
|
|
gptkbp:discoveredBy
|
gptkb:Tony_Hunter
|
|
gptkbp:discoveredIn
|
1986
|
|
gptkbp:Entrez_Gene_ID
|
GC06P111073
|
|
gptkbp:enzymeCommissionNumber
|
2.7.10.2
|
|
gptkbp:function
|
signal transduction
phosphorylation of tyrosine residues
|
|
gptkbp:gene
|
FYN
|
|
gptkbp:hasIsoform
|
FynB
FynT
|
|
gptkbp:HGNC_ID
|
HGNC:4037
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Fyn kinase
|
|
gptkbp:interactsWith
|
gptkb:PI3K
gptkb:FAK
gptkb:CD3
gptkb:p190_RhoGAP
gptkb:Lck
gptkb:NCAM
gptkb:Tau_protein
Cbp/PAG
p85 subunit
|
|
gptkbp:locatedOnChromosome
|
gptkb:6q21
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:member
|
gptkb:Src_family_kinases
|
|
gptkbp:OMIM
|
137025
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
2DQ7
|
|
gptkbp:phosphorylates
|
gptkb:FAK
gptkb:p190_RhoGAP
gptkb:CD3_zeta_chain
gptkb:NCAM
gptkb:Tau_protein
Cbp/PAG
|
|
gptkbp:RefSeq
|
NM_002037
|
|
gptkbp:UniProtID
|
P06241
|
|
gptkbp:bfsParent
|
gptkb:PTPN5
gptkb:B_cell_receptor_signaling_pathway
|
|
gptkbp:bfsLayer
|
7
|