|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:GSK3B
gptkb:GSK-3_beta
glycogen synthase kinase 3 beta
|
|
gptkbp:amendedBy
|
gptkb:cyclin_D1
gptkb:tau_protein
gptkb:CREB
gptkb:c-Jun
gptkb:NFAT
gptkb:c-Myc
gptkb:p53
gptkb:beta-catenin
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:diabetes
bipolar disorder
|
|
gptkbp:Entrez_Gene_ID
|
29123
|
|
gptkbp:enzymeCommissionNumber
|
EC 2.7.11.26
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
liver
|
|
gptkbp:fullName
|
gptkb:Glycogen_synthase_kinase-3_beta
|
|
gptkbp:function
|
serine/threonine-protein kinase
|
|
gptkbp:gene
|
gptkb:Gsk3b
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
rat Gsk3b
|
|
gptkbp:inhibitedBy
|
gptkb:Akt
gptkb:insulin
lithium
|
|
gptkbp:involves
|
gptkb:Wnt_signaling_pathway
glycogen metabolism
insulin signaling pathway
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
|
|
gptkbp:molecularWeight
|
46 kDa
|
|
gptkbp:organism
|
gptkb:Rattus_norvegicus
|
|
gptkbp:orthologIn
|
gptkb:mouse_Gsk3b
human GSK3B
|
|
gptkbp:phosphorylates
|
Ser9
Tyr216
|
|
gptkbp:regulates
|
gptkb:glycogen_synthase
apoptosis
cell proliferation
transcription factors
|
|
gptkbp:sequence
|
420 amino acids
|
|
gptkbp:subcellularLocation
|
gptkb:cell_membrane
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P49841
|
|
gptkbp:bfsParent
|
gptkb:GSK3β
|
|
gptkbp:bfsLayer
|
7
|