|
gptkbp:instanceOf
|
biological pathway
|
|
gptkbp:activatedBy
|
gptkb:PI3K
gptkb:B-Raf
PLC-epsilon
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Drosophila_melanogaster
|
|
gptkbp:hasComponent
|
gptkb:MAPK
gptkb:Rap1A
gptkb:Tiam1
gptkb:PI3K
gptkb:integrins
gptkb:cadherins
gptkb:Epac1
gptkb:Epac2
gptkb:p120-catenin
gptkb:B-Raf
gptkb:KRIT1
gptkb:RAPL
gptkb:RIAM
gptkb:beta-catenin
gptkb:E-cadherin
gptkb:VE-cadherin
afadin
AF-6
PDZ-GEF
PLC-epsilon
Rap1B
RapGAP
RapGEF1
Vav2
junctional adhesion molecules
tight junction proteins
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rap1 signaling pathway
|
|
gptkbp:involves
|
gptkb:Epac
gptkb:cAMP
gptkb:GAPs_(GTPase-activating_proteins)
gptkb:GEFs_(guanine_nucleotide_exchange_factors)
guanine nucleotide exchange factor
Rap1 protein
effectors
|
|
gptkbp:KEGGID
|
hsa04015
|
|
gptkbp:regulates
|
gptkb:MAPK_signaling_pathway
cell proliferation
cell migration
cell polarity
cell adhesion
cell junction formation
integrin-mediated signaling
|
|
gptkbp:relatedTo
|
gptkb:cancer
gptkb:cardiovascular_disease
immune response
|
|
gptkbp:bfsParent
|
gptkb:KRAS_(human)
gptkb:EPAC1
|
|
gptkbp:bfsLayer
|
7
|