|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:GTP-binding_protein_smg_p21A
gptkb:KREV-1
gptkb:RAP1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
leukemia
|
|
gptkbp:discoveredBy
|
gptkb:Pizon_et_al.
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:encodedBy
|
gptkb:RAP1A_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000116473
5906
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
regulation of cell adhesion
regulation of cell junction formation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasGeneCardsID
|
gptkb:RAP1A
|
|
gptkbp:hasGTPaseActivity
|
true
|
|
gptkbp:hasRefSeqID
|
NM_001010935
|
|
gptkbp:HGNC_ID
|
9856
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rap1A
|
|
gptkbp:interactsWith
|
gptkb:EPAC
gptkb:KRIT1
gptkb:RAP1GAP
gptkb:RIAM
gptkb:RasGEF1A
|
|
gptkbp:locatedOnChromosome
|
1p13.3
|
|
gptkbp:memberOf
|
gptkb:Ras_family
small molecule
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:OMIM
|
179530
|
|
gptkbp:orthologInMouse
|
gptkb:Rap1a
|
|
gptkbp:PDB
|
gptkb:1C1Y
gptkb:1GUA
1Q21
2Q21
|
|
gptkbp:postTranslationalModification
|
prenylation
phosphorylation
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
cell migration
integrin-mediated cell adhesion
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
gptkb:plasma_membrane
endosomes
|
|
gptkbp:UniProtID
|
gptkb:P62834
|
|
gptkbp:bfsParent
|
gptkb:Ral_guanine_nucleotide_dissociation_stimulator
|
|
gptkbp:bfsLayer
|
6
|