|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
autoimmune diseases
cancer metastasis
|
|
gptkbp:binds
|
gptkb:fibronectin
gptkb:collagen
gptkb:laminin
extracellular matrix proteins
|
|
gptkbp:component
|
gptkb:cell_membrane
|
|
gptkbp:composedOf
|
alpha subunit
beta subunit
|
|
gptkbp:discoveredBy
|
gptkb:Richard_O._Hynes
gptkb:Erick_Ruoslahti
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:example
|
gptkb:α5β1_integrin
gptkb:αIIbβ3_integrin
gptkb:αvβ3_integrin
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:function
|
signal transduction
cell adhesion
|
|
gptkbp:involvedIn
|
gptkb:immune_response
wound healing
cell migration
platelet aggregation
|
|
gptkbp:modulatedBy
|
cell signaling pathways
|
|
gptkbp:proteinFamily
|
gptkb:ITGA
gptkb:ITGB
|
|
gptkbp:relatedTo
|
cytoskeleton
focal adhesions
|
|
gptkbp:structure
|
heterodimer
|
|
gptkbp:target
|
therapeutic drugs
|
|
gptkbp:bfsParent
|
gptkb:PTK2
gptkb:FAK
gptkb:Laminin_alpha_chain
gptkb:RhoA_signaling_pathway
gptkb:ERK_pathway
gptkb:CD81
gptkb:SPP1
gptkb:L1CAM
gptkb:laminin
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
integrins
|