Epac2

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeName Exchange protein directly activated by cAMP 2
RAP guanine nucleotide exchange factor 4
gptkbp:associatedWith gptkb:type_2_diabetes
gptkbp:domain cAMP-binding domain
Ras exchange motif
gptkbp:encodedBy RAPGEF4 gene
gptkbp:expressedIn brain
pancreas
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function cAMP-regulated guanine nucleotide exchange factor
activates Rap1 and Rap2 GTPases
https://www.w3.org/2000/01/rdf-schema#label Epac2
gptkbp:locatedOnChromosome 2q31.1
gptkbp:location gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:OMIM 605197
gptkbp:role insulin secretion
neuronal signaling
gptkbp:UniProtID Q8WZA2
gptkbp:bfsParent gptkb:Epac
gptkbp:bfsLayer 7