Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
cyclic AMP
|
| gptkbp:discoveredBy |
gptkb:Jens_L._Bos
|
| gptkbp:discoveredIn |
1998
|
| gptkbp:encodedBy |
gptkb:RAPGEF3
gptkb:RAPGEF4 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
gptkb:Exchange_Protein_directly_Activated_by_cAMP
|
| gptkbp:function |
cAMP-regulated guanine nucleotide exchange factor
|
| gptkbp:gene |
gptkb:RAPGEF3
gptkb:RAPGEF4 |
| gptkbp:hasIsoform |
gptkb:Epac1
gptkb:Epac2 |
| https://www.w3.org/2000/01/rdf-schema#label |
Epac
|
| gptkbp:inhibitedBy |
gptkb:CE3F4
gptkb:ESI-09 |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:OMIM |
605525
|
| gptkbp:relatedTo |
gptkb:Rap1
gptkb:Rap2 PKA |
| gptkbp:role |
inflammation
cell adhesion cell junction formation insulin secretion neuronal signaling cardiac function |
| gptkbp:structure |
contains CDC25-homology domain
contains cAMP-binding domain |
| gptkbp:UniProtID |
O95398
Q8WZA2 |
| gptkbp:bfsParent |
gptkb:GEFs_(guanine_nucleotide_exchange_factors)
|
| gptkbp:bfsLayer |
6
|