Statements (59)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:healthcare_organization
|
| gptkbp:established |
gptkb:imatinib
gptkb:sunitinib gptkb:regorafenib ligand binding anti-PDGFR-alpha antibodies |
| gptkbp:form |
PDGFR-alpha isoform 1
PDGFR-alpha isoform 2 |
| gptkbp:function |
receptor for platelet-derived growth factor
|
| gptkbp:has_role |
wound healing
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDGFR-alpha
|
| gptkbp:interacts_with |
PDGF
|
| gptkbp:is_aimed_at |
monoclonal antibodies
|
| gptkbp:is_associated_with |
poor prognosis
|
| gptkbp:is_involved_in |
gptkb:psychologist
gptkb:embryonic_development cell differentiation cell proliferation immune response metabolic disorders autoimmune diseases fibrosis muscle regeneration tissue engineering cardiovascular diseases bone healing chronic kidney disease tumor microenvironment extracellular matrix remodeling pulmonary hypertension pulmonary fibrosis organogenesis angiogenesis atherosclerosis chronic inflammation vascular remodeling placental development tissue repair cell migration metastasis stem cell maintenance development of the nervous system hair follicle development tumor angiogenesis endothelial cell function diabetes complications cartilage repair fibroblast activation liver fibrosis skin fibrosis smooth muscle cell function |
| gptkbp:is_part_of |
signal transduction pathway
|
| gptkbp:is_represented_in |
gptkb:healthcare_organization
mesenchymal cells |
| gptkbp:located_in |
cell membrane
|
| gptkbp:promoter |
PDGFRA
|
| gptkbp:bfsParent |
gptkb:PDGFR
|
| gptkbp:bfsLayer |
6
|