idiopathic hypereosinophilic syndrome

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:syndrome gptkb:disease
gptkbp:affects	gptkb:skin gptkb:nervous_system lungs gastrointestinal tract cardiac system hematologic system
gptkbp:causedBy	gptkb:unknown
gptkbp:complication	heart failure fibrosis thromboembolism
gptkbp:firstDescribed	1968
gptkbp:hasDiagnosticCriteria	persistent eosinophilia >1500/μL for more than 6 months absence of identifiable cause evidence of organ involvement
gptkbp:hasOrphanetID	gptkb:ORPHA:324
gptkbp:ICD-10_code	gptkb:D72.1
gptkbp:inheritance	sporadic
gptkbp:MeSH_ID	gptkb:D006967
gptkbp:mortalityRate	can be fatal if untreated
gptkbp:prevalence	rare
gptkbp:prognosis	variable
gptkbp:symptom	fever fatigue weight loss cough shortness of breath skin rash neurological symptoms eosinophilia cardiac involvement
gptkbp:synonym	gptkb:HES idiopathic HES
gptkbp:treatment	gptkb:interferon-alpha gptkb:hydroxyurea gptkb:imatinib corticosteroids
gptkbp:bfsParent	gptkb:Pdgfra gptkb:PDGFR-alpha gptkb:PDGFRα
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	idiopathic hypereosinophilic syndrome