MYB proto-oncogene, transcription factor

URI: https://gptkb.org/entity/MYB_proto-oncogene,_transcription_factor
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs gptkb:c-Myb
gptkb:MYB
gptkbp:associatedWith gptkb:cancer
gptkb:acute_myeloid_leukemia
colorectal cancer
gptkbp:discoveredBy gptkb:Thomas_Graf
gptkbp:domain DNA-binding domain
gptkbp:encodes gptkb:Myb_protein
gptkbp:Entrez_Gene_ID 4602
gptkbp:expressedIn hematopoietic cells
breast tissue
colon epithelium
gptkbp:firstDescribed 1982
gptkbp:function transcription factor
gptkbp:HGNC_ID 7545
https://www.w3.org/2000/01/rdf-schema#label MYB proto-oncogene, transcription factor
gptkbp:locatedOnChromosome 6q23.3
gptkbp:mutationAssociatedWith gptkb:cancer
leukemia
gptkbp:orthologInMouse Myb
gptkbp:regulates gptkb:MYB_family
apoptosis
cell differentiation
cell proliferation
gene expression
cell cycle
hematopoiesis
gptkbp:targetGene gptkb:CDKN1A
gptkb:CCNB1
gptkb:CD34
gptkb:GATA3
gptkb:IL6
gptkb:KITLG
gptkb:MCL1
gptkb:MIM1
gptkb:NR4A1
gptkb:PRDM1
gptkb:ZBTB16
gptkb:VEGFA
gptkb:CDK6
gptkb:BCL2
gptkb:FOS
gptkb:MYC
gptkb:RUNX1
gptkb:TP53
gptkbp:UniProtID P10242
gptkbp:bfsParent gptkb:MYB
gptkbp:bfsLayer 6