MYB proto-oncogene, transcription factor

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:gene
gptkbp:alsoKnownAs	gptkb:c-Myb gptkb:MYB
gptkbp:associatedWith	gptkb:cancer gptkb:acute_myeloid_leukemia colorectal cancer
gptkbp:discoveredBy	gptkb:Thomas_Graf
gptkbp:domain	DNA-binding domain
gptkbp:encodes	gptkb:Myb_protein
gptkbp:Entrez_Gene_ID	4602
gptkbp:expressedIn	hematopoietic cells breast tissue colon epithelium
gptkbp:firstDescribed	1982
gptkbp:function	gptkb:transcription_factor
gptkbp:HGNC_ID	7545
gptkbp:locatedOnChromosome	6q23.3
gptkbp:mutationAssociatedWith	gptkb:leukemia gptkb:cancer
gptkbp:orthologInMouse	Myb
gptkbp:regulates	gptkb:MYB_family apoptosis cell differentiation cell proliferation gene expression cell cycle hematopoiesis
gptkbp:targetGene	gptkb:CDKN1A gptkb:CCNB1 gptkb:CD34 gptkb:GATA3 gptkb:IL6 gptkb:KITLG gptkb:MCL1 gptkb:MIM1 gptkb:NR4A1 gptkb:PRDM1 gptkb:ZBTB16 gptkb:VEGFA gptkb:CDK6 gptkb:BCL2 gptkb:FOS gptkb:MYC gptkb:RUNX1 gptkb:TP53
gptkbp:UniProtID	P10242
gptkbp:bfsParent	gptkb:MYB
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	MYB proto-oncogene, transcription factor