|
gptkbp:instanceOf
|
gptkb:disease
gptkb:skin
leukemia
|
|
gptkbp:abbreviation
|
ALL
|
|
gptkbp:affects
|
gptkb:skin
gptkb:T-cells
adults
blood
bone marrow
lymphoid lineage
|
|
gptkbp:alternativeName
|
acute_lymphoblastic_leukemia
cutaneous_T-cell_lymphoma
hematologic_malignancy
leukaemia
lymphoma
non-Hodgkin_lymphoma
|
|
gptkbp:cause
|
gptkb:anemia
infections
lymphadenopathy
neutropenia
thrombocytopenia
organomegaly
|
|
gptkbp:causedBy
|
unknown
|
|
gptkbp:commonIn
|
children
|
|
gptkbp:diagnosedBy
|
blood test
bone marrow biopsy
cytogenetic analysis
immunophenotyping
skin biopsy
flow cytometry
molecular testing
|
|
gptkbp:firstDescribed
|
1806
|
|
gptkbp:hasOrphanetID
|
99860
|
|
gptkbp:hasRelapseRate
|
higher in adults
|
|
gptkbp:hasRemissionRate
|
high in children
|
|
gptkbp:hasSurvivalRate
|
lower in adults
over 85% in children
|
|
gptkbp:hasTreatmentPhase
|
maintenance
induction
consolidation
CNS prophylaxis
|
|
gptkbp:hasTypicalOnset
|
childhood
adolescence
|
|
gptkbp:ICD-10_code
|
gptkb:C91.0
C84
|
|
gptkbp:mayInclude
|
central nervous system
testes
|
|
gptkbp:MeSH_ID
|
gptkb:D015458
|
|
gptkbp:mortalityRate
|
variable
higher in adults
|
|
gptkbp:OMIM
|
613065
|
|
gptkbp:originatedIn
|
T lymphocyte
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
variable
depends on stage
|
|
gptkbp:riskFactor
|
gptkb:Down_syndrome
radiation exposure
genetic predisposition
older age
male gender
weakened immune system
|
|
gptkbp:subspecies
|
gptkb:B-cell_ALL
gptkb:T-cell_ALL
gptkb:mycosis_fungoides
gptkb:Sézary_syndrome
|
|
gptkbp:symptom
|
fever
bleeding
fatigue
rash
bone pain
pallor
skin lesions
enlarged lymph nodes
itchy skin
|
|
gptkbp:treatment
|
radiation therapy
chemotherapy
immunotherapy
phototherapy
targeted therapy
stem cell transplant
topical corticosteroids
|
|
gptkbp:bfsParent
|
gptkb:Charles_Lindbergh
gptkb:Dave_Prichard
gptkb:David_Marr
gptkb:Denise_Levertov
gptkb:Dick_Fosbury
gptkb:Irène_Joliot-Curie
gptkb:Julius_Nyerere
gptkb:King_Hussein_of_Jordan
gptkb:Paul_Allen
gptkb:Rainer_Maria_Rilke
gptkb:Richard_Smalley
gptkb:cancer
gptkb:Ronald_Dworkin
gptkb:Roman_Reigns
gptkb:Frantz_Fanon
gptkb:Leonard_Cohen
gptkb:Edward_Said
gptkb:Louis_Malle
gptkb:Anthony_Hecht
gptkb:Charles_Tilly
|
|
gptkbp:bfsLayer
|
4
|