|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:BLIMP-1
|
|
gptkbp:associatedWith
|
gptkb:immunodeficiency
multiple myeloma
diffuse large B-cell lymphoma
|
|
gptkbp:domain
|
zinc finger domain
PR domain
|
|
gptkbp:encodes
|
gptkb:PR_domain_zinc_finger_protein_1
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000119715
639
|
|
gptkbp:expressedIn
|
gptkb:lymphoid_tissue
plasma cells
|
|
gptkbp:function
|
transcriptional repressor
|
|
gptkbp:HGNC_ID
|
9346
|
|
gptkbp:interactsWith
|
gptkb:HDAC2
gptkb:IRF4
gptkb:CBFA2T3
gptkb:G9a
gptkb:PU.1
|
|
gptkbp:involvedIn
|
B cell differentiation
plasma cell differentiation
|
|
gptkbp:length
|
825 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:6q21
|
|
gptkbp:molecularWeight
|
approximately 91 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:leukemia
gptkb:autoimmune_disease
|
|
gptkbp:orthologInMouse
|
gptkb:Prdm1
|
|
gptkbp:regulates
|
gptkb:interferon-beta
gptkb:c-Myc
gptkb:immune_response
gptkb:CIITA
gptkb:PRDM_family
gptkb:PAX5
gptkb:BCL6
apoptosis
cell proliferation
inflammatory response
cytokine production
germinal center reaction
immune tolerance
T cell homeostasis
T cell exhaustion
immunoglobulin genes
terminal differentiation of B cells
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:O75626
|
|
gptkbp:bfsParent
|
gptkb:MYB_proto-oncogene,_transcription_factor
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRDM1
|