KITLG

URI: https://gptkb.org/entity/KITLG

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:gene
gptkbp:alsoKnownAs	gptkb:SCF gptkb:mast_cell_growth_factor gptkb:steel_factor gptkb:stem_cell_factor
gptkbp:discoveredBy	T. Williams et al.
gptkbp:encodes	gptkb:KIT_ligand_protein
gptkbp:Entrez_Gene_ID	4254 ENSG00000157404
gptkbp:expressedIn	gptkb:skin bone marrow gonads
gptkbp:firstDescribed	1990
gptkbp:fullName	gptkb:KIT_ligand
gptkbp:function	regulates cell survival, proliferation, and differentiation essential for hematopoiesis involved in gametogenesis involved in melanogenesis
gptkbp:geneLocationEnd	88,684,964
gptkbp:geneLocationStart	88,654,964
gptkbp:geneType	protein-coding
gptkbp:hasTranscriptVariant	multiple
gptkbp:HGNC_ID	HGNC:6342
gptkbp:length	273 amino acids
gptkbp:locatedOnChromosome	12q21.32
gptkbp:mutationAssociatedWith	gptkb:familial_progressive_hyperpigmentation gptkb:piebaldism testicular germ cell tumor susceptibility
gptkbp:OMIM	184745
gptkbp:orthologInMouse	gptkb:Kitlg
gptkbp:pathway	gptkb:Hematopoietic_cell_lineage gptkb:Melanogenesis gptkb:MAPK_signaling_pathway gptkb:PI3K-Akt_signaling_pathway
gptkbp:recipient	gptkb:c-KIT_(CD117)
gptkbp:species	gptkb:Homo_sapiens
gptkbp:UniProtID	P21583
gptkbp:bfsParent	gptkb:MYB_proto-oncogene,_transcription_factor
gptkbp:bfsLayer	7
http://www.w3.org/2000/01/rdf-schema#label	KITLG