BCL2L11

GPTKB entity

Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias BIM
BCL2-interacting mediator of cell death
BCL2-like 11
gptkbp:alternativeSplicing produces multiple isoforms
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
gptkbp:component mitochondrion
gptkbp:encodes BIM protein
gptkbp:Entrez_Gene_ID 10018
ENSG00000153094
gptkbp:expressedIn gptkb:thymus
spleen
bone marrow
lymphoid tissues
gptkbp:function pro-apoptotic protein
BH3 domain binding
gptkbp:GOProcess intrinsic apoptotic signaling pathway
gptkbp:HGNC_ID 994
https://www.w3.org/2000/01/rdf-schema#label BCL2L11
gptkbp:interactsWith gptkb:MCL1
gptkb:BAX
gptkb:BAK1
gptkb:BCL2
gptkb:BCL2L1
gptkbp:locatedOnChromosome 2q13
gptkbp:memberOf BCL-2 protein family
gptkbp:organism gptkb:Homo_sapiens
gptkbp:regulates apoptosis
phosphorylation
ubiquitination
proteasomal degradation
gptkbp:UniProtID O43521
gptkbp:bfsParent gptkb:MCL1
gptkb:BCL2_family
gptkb:BCL2
gptkbp:bfsLayer 7