|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
BIRC4
ILP1
hILP
|
|
gptkbp:associatedWith
|
X-linked lymphoproliferative syndrome type 2
|
|
gptkbp:binds
|
gptkb:caspase-9
gptkb:caspase-3
gptkb:caspase-7
|
|
gptkbp:discoveredBy
|
1996
|
|
gptkbp:domain
|
RING finger domain
BIR domain
|
|
gptkbp:Entrez_Gene_ID
|
331
ENSG00000101966
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
X-linked inhibitor of apoptosis protein
|
|
gptkbp:function
|
E3 ubiquitin-protein ligase activity
inhibits apoptosis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:XIAP
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
XIAP
|
|
gptkbp:inhibitedBy
|
caspase activity
|
|
gptkbp:interactsWith
|
gptkb:TAK1
gptkb:TAB1
SMAC/DIABLO
|
|
gptkbp:length
|
497
|
|
gptkbp:locatedOnChromosome
|
X
|
|
gptkbp:location
|
Xq25
|
|
gptkbp:molecularWeight
|
56 kDa
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
inflammatory bowel disease
|
|
gptkbp:OMIM
|
300079
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Xiap
|
|
gptkbp:PDB
|
1C9Q
1I3O
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:proteinFamily
|
IAP family
|
|
gptkbp:regulates
|
immune response
cell death
NF-kappaB signaling
MAPK signaling
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
mitochondria
|
|
gptkbp:UniProtID
|
P98170
|
|
gptkbp:bfsParent
|
gptkb:Caspase-9
|
|
gptkbp:bfsLayer
|
7
|