Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:Caspase-9
gptkb:Caspase-8 |
| gptkbp:alsoKnownAs |
gptkb:Caspase-3
|
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases |
| gptkbp:cleavage |
DEVD peptide sequence
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:EC_number |
3.4.22.56
|
| gptkbp:encodedBy |
CASP3 gene
|
| gptkbp:Entrez_Gene_ID |
836
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:form |
heterotetramer
|
| gptkbp:function |
cysteine-aspartic acid protease
|
| https://www.w3.org/2000/01/rdf-schema#label |
CPP32
|
| gptkbp:inhibitedBy |
gptkb:XIAP
|
| gptkbp:involvedIn |
apoptosis
|
| gptkbp:locatedOnChromosome |
4q34
|
| gptkbp:molecularWeight |
32 kDa
|
| gptkbp:OMIM |
600636
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:1PAU
|
| gptkbp:role |
execution-phase of cell apoptosis
|
| gptkbp:structure |
contains large and small subunits
|
| gptkbp:substrate |
gptkb:ICAD
poly(ADP-ribose) polymerase (PARP) |
| gptkbp:UniProtID |
P42574
|
| gptkbp:bfsParent |
gptkb:P49918
|
| gptkbp:bfsLayer |
7
|