Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
apoptosis inhibitors
|
| gptkbp:discoveredIn |
gptkb:Drosophila_melanogaster
|
| gptkbp:domain |
RING finger domain
BIR domain |
| gptkbp:encodedBy |
BIRC genes
|
| gptkbp:foundIn |
animals
humans |
| gptkbp:fullName |
Inhibitor of Apoptosis Proteins
|
| gptkbp:function |
inhibit apoptosis
regulate cell death |
| https://www.w3.org/2000/01/rdf-schema#label |
IAP proteins
|
| gptkbp:inhibitedBy |
gptkb:caspases
|
| gptkbp:member |
gptkb:Livin
gptkb:XIAP gptkb:cIAP1 gptkb:cIAP2 BRUCE NAIP Survivin |
| gptkbp:orthologIn |
insects
mammals |
| gptkbp:proteinFamily |
BIRC
|
| gptkbp:regulates |
inflammatory response
NF-kB signaling |
| gptkbp:role |
gptkb:cancer
cell survival immune response |
| gptkbp:target |
Omi/HtrA2
Smac/DIABLO |
| gptkbp:therapeuticArea |
gptkb:cancer
|
| gptkbp:bfsParent |
gptkb:Caspase
gptkb:caspases |
| gptkbp:bfsLayer |
7
|